Widower Michael Bluth has been working for his father's development company since he was a teenager manning the family's frozen banana stand, and he and his son George Michael have gone so far as to move into one of the company's model homes. So when his father George Sr. throws his retirement party on the family yacht, Michael expects that he will be announced as his father's successor. Instead, Michael gets two surprises: His mother is the new President, and his father is under investigation by the SEC. So Michael has to hold his wildly dysfunctional family together.
Michael suspects that George Sr. is running the business from inside prison. George Michael is made manager of the banana stand, and Michael gives GOB a letter to mail after Lucille suggests that he be included in the business.
Lucille suggests that Buster be included in the family activities, but Buster is reluctant to leave his mother's apartment in hopes of avoiding Lucille 2. Meanwhile, Tobias takes over the directing duties for the high school play to rather disastrous results.
Determined to not be upstaged by his actress girlfriend, GOB decides to pull an elaborate escape at the Orange County Prison, where George Sr. is being held. Meanwhile, Michael falls for GOB's girlfriend Marta.
To help the company's image, Lindsay returns to her roots - charity fund raisers. While Lindsay is the most charitable member of the family, Michael tries to prove he's a more charitable person by helping a woman he thinks is his mother's housekeeper. Maebe, defying her parents, decide to break into the permit office, using George-Michael's help, and they learn a shocking secret about the Bluth Company. Meanwhile, Buster accidentally bids on his mother's social rival Lucille Austero at a charity bachelorette auction.
Michael gets a tip about the company's international accounts, and has GOB question the office secretary Kitty about them. But that's not before Michael does the unthinkable - setting up a conjugal visit between George Sr. and Lucille.
It's time for the annual Living Classics Pageant, and Barry makes a deal with Michael to get George Sr. out in time to take part in the pageant's signature exhibit - Michaelangelo's The Creation Of Adam. But there is no god when George Sr. makes plans to escape.
Michael cannot remember anything about the car accident he and Lucille were in. While he's trying to piece together the accident, GOB thinks Michael is planning to escape to South America with his father. Meanwhile, Lindsay makes repeated visits to the prison in hopes of scoring a date.
Determined to get back in the Magician's Alliance, GOB puts on one last big show, thanks to his brother Michael. Michael, hoping to steal Marta away from GOB, tries to pull a scam almost as great as GOB's magic act. Meanwhile, Tobias, hoping to impress his daughter, becomes a “leather daddy”.
When Michael suspects that George Michael has been smoking marijuana, he enlists the help of a one-armed man his father used to scare them as children. GOB and Buster participate in the bust, which also enlists the help of a local stripper agency.
The family's new public relations director gives them each a task while Michael tries to get his son in the prestigious Milford Academy. Buster, a graduate, is to be neither seen nor heard. Tobias heads to Boston to get his medical license back, only to meet Carl Weathers on the way there, and GOB makes the academy's founder disappear.
It's Valentine's Day and everyone but Michael has a reason to celebrate. Buster, tired of dealing with his mother, goes to live with the rest of the family in the model home. But soon Marta realizes that Michael is the one she has feelings for, not GOB.
After Tobias moves into his room, George Michael gets a rather curious tip about his cousin's origins, so he decides to investigate. GOB, worried about his girlfriend Marta, heads down to the TV studio to visit the set of her show, to confront a man named “Hermano”.
George Sr. starts his own line of priced-to-own videotapes after he experiences a religious revelation during a stay in solitary confinement. A fan of his visits, but not after George Sr. learns that she's with the prosecution. Meanwhile, Michael falls for George-Michael's ethics teacher.
Michael is tired of the family getting free handouts from the Bluth Company without doing anything, so he puts them to work. He puts Lindsay to work at the company answering phones, while GOB and Buster take construction jobs. Meanwhile, the sheep-like behavior of the Bluth Company employees gets them in trouble on a visit to the island of Catalina, and Tobias, researching his role as a frightened inmate, checks himself into the prison where George Sr. is being held.
Micheal has a one-night stand with a woman named Maggie Lizer. He has a guilt-trip after learning she is blind, but not so much after he discovers that she's the prosecuting attorney against his family. Meanwhile, GOB gets married to a woman after a series of escalating dares, and tries to get a subsequent divorce.
Michael gets an evidence file about his family after sleeping with the Maggie Lizer, the prosecuting attorney. But he suspects that she's not exactly telling the truth, so he sends Tobias to her house to investigate, who finds out that she's not blind. Meanwhile, GOB's divorce does not go as smoothly as planned.
Spring Break hits Orange County, and GOB plans to take his magic act to the popular video series “Girls With Low Self Esteem” by making the family yacht disappear. Michael becomes concerned that George-Michael is spending too much time with GOB, so he puts George Michael to work at the Bluth Company. Kitty threatens to go to court with evidence against the company. Meanwhile, Lindsay and Maeby investigate the whereabouts of their grandmother, and Lucille's newly adopted Korean son Annyong annoys the family.
The family accountant, Ira Gilligan, is planning to snitch, and George Sr. will do everything possible to stop him. He enlists GOB to throw a party, where he will try to make Ira flee the country to avoid testifying. Michael and his son plan a fishing trip, while Tobias wants to reunite a folk band he formed with Lindsay and Maeby to promote pharmaceuticals.
Some company funds have been unfrozen, and everyone in the family wants a cut of it. Michael makes a bad investment on his uncle Oscar's land, and takes the blame for it. Meanwhile George Michael spots a mysterious man who looks a lot like his grandfather, and the Bluth Company institutes a new whistle-blowing policy.
Michael decides that it's time to retire a long-running joke involving George-Michael and “Take Your Daughter To Work Day”, so he brings Maeby along for the ride instead. The police get involved in the disappearance of Kitty Sanchez, the company's former secretary, and Michael discovers shocking video evidence of Kitty's last known whereabouts.
Michael learns the real secret behind the Bluth Company's international accounts - his dad may have been illegally building houses similar to the one he lives in in Iraq. George Sr. agrees to take a lie detector test to prove his innocence, but the family gets word that he has had a heart attack while in prison. The family goes to the hospital to visit, but learns that George Sr. has made an elaborate escape. Michael decides that he's had enough, and he and George-Michael decide to pack up and head to Phoenix.