Based on the wildly popular comic book series “Hellblazer” from DC Comics, seasoned demon hunter and master of the occult John Constantine is armed with a ferocious knowledge of the dark arts and a wickedly naughty wit. He fights the good fight - or at least he did. With his soul already damned to hell, he's decided to abandon his campaign against evil until a series of events thrusts him back into the fray when an old friend's daughter becomes the target of supernatural forces.
Deep in the mountains of Western Pennsylvania, John is the small mining community's only defense against an ancient Welsh spirit. In the course of protecting these isolated innocents, John finds a vital new ally in a mysterious young woman named Zed.
John and Zed engage in a dangerous confrontation to save a woman and her family from sinister forces. John's efforts force him to confront the darkness in his own life - while also coming face to face with a new powerful adversary in Papa Midnite.
When Constantine's old friend Gary Lester accidentally releases a powerful demon in Atlanta, John is forced to determine exactly what he is prepared to sacrifice in his battle with the underworld.
In New Orleans, Constantine's unusual knowledge of a string of crimes gets him into trouble with Detective Jim Corrigan. He must form an unholy alliance with Papa Midnite when a voodoo ritual to help people communicate with their dead loved ones takes a deadly turn.
When a young boy is taken over by a malevolent spirit, John must put aside his misgivings over exorcising a child and convince the parents that their boy is not all that he seems.
While in art class, Zed has a bizarre vision of snakes that lead her and John to a small town where a preacher has mysteriously gained the ability to heal his congregation.
Anne Marie, a member of the Newcastle crew, asks John and Chas for help in Mexico City – bringing them close to the heart of the rising darkness; Zed is haunted by her past.
John summons a demon into himself to help fend off an attack; Chas, Zed, and Anne Marie rush to save John.
When thousands of people in Brooklyn - including Chas' daughter - slip into comas, John must locate and defeat the evil forces responsible.
John is sent to help an old friend at Ivy University, where students have figured out how to get to an alternate dimension - only to be met by a killer.
John asks Manny to help him investigate a mysterious attack at a hospital; a health issue prompts Zed to question her visions.
John and Zed return to New Orleans when Detective Jim Corrigan asks for their help in the case of a missing girl. Papa Midnite takes steps toward exacting his revenge on John. Meanwhile, the truth behind the Rising Darkness comes to light.