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After Alan falls off the roof, Charlie has to look after the adolescent and increasingly obnoxious Jake for the weekend.
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Alan has to lobby the principal to keep Jake from getting expelled, while Charlie is left to manage the chiropractic office for the day.
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After it's revealed Alan and Judith have been trying to reconcile, Charlie, Evelyn, and Rose vie for the role of spoiler.
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Alan looks for a new place after he invites Berta to stay at Charlie's house, bringing the brothers to blows.
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Charlie's inability to reciprocate his girlfriend's love forces him to examine his relationships with women.
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Charlie's Satan-worshiping girlfriend has a knack for the supernatural, and seems to be the cause of some strange happenings around the Harper house.
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Charlie gets drunk and sleeps with Rose on her birthday. Rose says she knows it's no big deal. But her father quickly shows up at Charlie's house, under the impression that they've been dating for two years.
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Charlie bribes Jake into taking ballet lessons so he can vie for the affections of the teacher. Things go awry, however, when Charlie and Jake find themselves competing for those affections.
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Charlie's elderly neighbor has an uncomfortable business proposition for Alan.
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After Alan goes on a dinner with Jake, Charlie and Evelyn, he becomes fed up with seeking approval from women and decides to quit doing so with a little help from Charlie.
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Alan's girlfriend Sandy is Malibu's answer to Martha Stewart, causing Alan and Charlie to pack on the pounds. Their desire for her fabulous culinary output is ultimately overwhelmed by her craziness.
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After a disastrous evening out with his brother, Charlie decides it is time to see a shrink.
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Charlie has to decide whether he can really commit to a serious relationship with Mia, especially when sex is currently off the agenda. Unsurprisingly, his suggestion that he sleep with other women in the meantime falls on somewhat stony ground.
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As Charlie tries to receive his version of benefits from the relationship he has with Mia, Alan starts dating Charlie's most recent ex-girlfriend.
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Forced to hide in his garage to enjoy a brace of beers and half a Cuban cigar, Charlie's attempts to keep his unhealthy lifestyle habits secret from Mia fall apart when she smells bacon on his breath, resulting in their first major argument since taking their relationship to a physical plane.
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Jake's twelfth birthday approaches. Alan is busy with young, hot Kandi.
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Charlie is nominated for an award, but he knows his rival Archie will win, as usual, so he doesn't want to attend it. Rose asks Charlie to help her with her boyfriend Gordon.
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Alan is having financial problems: Kandi is too “expensive” for him.
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Charlie learns that Kandi has been living with them for three weeks. It turns out he hasn't even noticed some furniture changes. Alan wants to try her as secretary, but Charlie doesn't think she's smart enough for that.
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Alan is made to admit to Charlie, who keeps hitting it in, he has hit rock-bottom now his brainless girlfriend Kandi has moved in with his ex. It's all so confusing that Jake would prefer dad's ladies to be lesbians, then tells him Kandi's ma Mandi has joined Charlie's endless list of sexual conquests. Alan can't talk to Kandi, she just repeats Judith's phrases, clearly without understanding the words, but he sees her dad, Mandi's ex Andy, arrive on blind date with his own ex Judith. Frolicking finale at Judith's, in rooms, bed and hot-tub…
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Alan turns to Jake's teacher for stimulating conversation, since Kandi obviously can't provide any. But the teacher starts to get the wrong idea about Alan's intentions.
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Jake has his first boys-girls party, dating a smart girl, Wendy Cho. Alan was looking forward to coaching his son, but even Jake, who spends his schooldays watching the clock tick, isn't dumb enough to consider dating advice from the worst womanizer in L.A., while Charlie proves he can coach a virtually hopeless case -Alan and Judith's genes without the IQ- trough appearance, dance and anything else. In fact Alan envies Jake so much, he still hopes for …
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Mia comes back and asks Charlie to donate his sperm. He agrees to, but for some unknown reason he can't deliver.
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Charlie and Mia discover that setting up a wedding with their two crazy families is a disaster, so they decide to get married in Las Vegas.