While the unit tackles a murder case involving a woman who stole a million dollars from her employer, Patrick finds out that they have been removed from the Red John case.
While CBI investigates the murder of a California state senator's aide, Patrick works on his own under the assumption that the victim was having an affair with a member of the senator's family.
A child rapist from agent Lisbon's past is shot and killed. The evidence points to Lisbon herself, but she has no recollection of the night in question.
The team investigates a dangerous biker gang in order to gather information about the death of the attorney who represented the gang.
An architect is killed in the old mansion he recently bought, and the investigation reveals rumors of a haunted house and hidden treasure, as well as the angry descendants of the original owner.
While CBI investigates a homicide over what appears to be over a land claim, Patrick is put in jail for spying on Sam Bosco to get information on Red John.
Patrick and the rest of the CBI team is forced to work together with Patrick's nemesis in the office, Sam Bosco, in order to find a kidnapping victim.
Red John strikes again, this time in the CBI office, leaving three agents dead and Sam Bosco in critical condition.
The new husband of a jewelry store owner is critically injured accidentally walking in on a jewel heist. CBI soon suspects that the heist was pulled off with help from the inside–specifically one of the owner's two nephews.
The founder of a prestigious Baseball Academy is murdered. Jane is hit by a baseball as the investigation begins, and he recalls his teenage years as a carnival psychic.
A former high school student and his wife are killed before his high school reunion, and Jane is forced to get Rigsby's help to perform an elaborate ruse to find the killer.
While investigating the death of a mayor's media liaison, Patrick is kidnapped by an eco-terrorist who is a suspect in the case. Meanwhile, the team reluctantly agrees to be filmed for a documentary.
Patrick Jane and the CBI team investigate when the body of a high-end luxury car sales woman is found in the trunk of a Bentley in the dealership's showroom.
When a member of Cho's former gang, the Avon Park Playboys, is found murdered, Patrick Jane insists on helping Cho with his off-the-books investigation.
A chef is poisoned to death during a competition, and CBI is forced to find his killer among his competitors, his estranged wife, and his ambitious assistant.
The leak of a dangerous virus at a bio-research facility results in the death of a scientist, and Lisbon and Jane clash with a Disease Control official when they decide to treat the death as a homicide.
While the team investigates the murder of an English tutor who stole a valuable artifact from a British museum, the new boss comes in and lays down the law.
Patrick is forced to turn to a woman with amnesia to help solve a murder case on an Indian reservation, while special agent Hightower delivers an ultimatum to Rigsby and Van Pelt about their personal relationship.
Patrick's reckless behavior catches up with him when his actions get a case against a hitman thrown out of court and Lisbon on suspension. But when the hitman his shot and killed, he has a shot at redemption.
Patrick finds a new adversary in a charismatic but manipulative cult leader while the CBI team investigates the death of the CEO of a media conglomerate.
A brilliant mathematician is shot and killed by a clown, and the team discovers that he was working on a priceless code-breaking device.
A man is murdered right before he is to deliver an important speech about human trafficking at a conference. Psychic Kristina Frye is brought in to help CBI solve the case, even though Patrick remains skeptical about her “gift.”
The tension between Patrick and Kristina escalates when a Red John impostor strikes and Kristina offers her services to the CBI. However, the case causes the real Red John to come back and meet Patrick for the first time face-to-face.