Stewie and Brian explore a series of alternate universes.
When Peter and Lois find out that Lois' mother was a Holocaust survivor, Peter decides that the Griffins will adopt the Jewish faith, until a vision of his dead father changes his mind.
With the help of Chevy Chase and Dan Aykroyd, Stewie and Brian discover that mayor Adam West is a Cold War sleeper agent. Meanwhile, Peter, Quagmire, and Joe start an improv comedy group.
When Brian snags an older woman, he's the laughingstock of the family, but things get really bad when she breaks her hip and Brian has to be her errand-boy.
Brian helps Stewie meet Miley Cyrus before her concert in Quahog, and they discover a secret about her identity. Meanwhile, the family discovers that the evil monkey in Chris's closet isn't actually evil.
Quagmire is forced to take care of a baby he fathered when she is left on his doorstep, while Stewie creates clones of himself and Brian.
The guys find a new black friend to join their group, until Peter finds out that he slept with Lois. Meanwhile, Brian tries to find out why Quagmire hates him and tries to make amends.
When Brian accidentally kills another dog he is surprised to see that no one cares so he tries to convince everyone that the life of a dog should have the same value as a human one. Meanwhile, Lois hires a maid who doesn't listen to Peter.
Peter takes over Pewterschmidt Industries when his father-in-law has a heart attack and goes into a coma.
The Griffins are invited to be contestants on the game show “Family Feud.” After winning the game and advancing to the show's bonus round (called Fast Money), Lois puts the Griffins in prime position to win the game, but Peter bungles the opportunity when he stubbornly refuses to change his answer to the first question. Host Richard Dawson tries to remind Peter of the rules, but when Peter continues to argue and grabs Dawson, he gets pushed through a podium on the set and is knocked unconscious. At the hospital, Dr. Hartman tells Lois that Peter has amnesia. At home, …
Meg goes to prison after her boyfriend escapes from jail, and returns as a frightening, hardened sociopath.
After they are saved after being lost in the wilderness, Stewie helps Chris muster up the courage to ask a girl with Down Syndrome out on a date, while Peter pretends to be a psychic.
Stewie poses as a girl so that he can appear on a children's show, but trouble arises when he falls for a female co-star. Meanwhile, Meg gets a new boyfriend, but Lois tries to make a move on him.
Peter is sexually harassed by his unattractive female boss, but will he follow through with her advances and keep his job?
Brian sells his pilot for a heartwarming family drama to CBS, who then turns it into a lame, formulaic sitcom starring James Woods. Meanwhile, Meg and Chris try to hide Stewie's accidental injury they caused from their parents.
Peter makes an embarrassing confession about his kids as everyone thinks the world is about to come to an end.
In the Special 1-Hour 150th Episode Event, Brian and Stewie get locked in a bank vault where they are forced to deal with each other on a whole new level. The one-hour event also includes never-before-seen musical footage.
Quagmire's dad comes to Quahog and announces that he's undergoing a sex change. And when Brian returns to town after a seminar, he accidentally makes the situation even more awkward.
With Cleveland's help, Peter, Joe and Quagmire blow off a couples getaway to Maine to search for the origin of the worlds funniest dirty joke.
While being chased by Darth Vader (Stewie) on the planet Hoth, young Luke Skywalker (Chris) has a vision of his dead mentor Obi-Wan Kenobi (Herbert), who tells him to go to the planet Dagobah and learn the ways of the Force from Jedi Master Yoda (Carl). Luke has a vision of the Empire capturing his friends and forgoes his Jedi training in order to save them by confronting Vader. Luke arrives at Cloud City and engages Vader in a lightsaber duel. Vader cuts off Luke's right hand, and with Luke cornered and defenseless, Vader goads him to join the dark side, and then reveals that he is his father.
Lois agrees to become a surrogate mother for a friend who is unable to conceive a child of her own. But when the friend and her husband are killed in a car accident, Lois and Peter consider whether to terminate the pregnancy.