When a car careens out of control over an embankment, killing a middle-aged man in the driver's seat, Megan learns that all is not well on a pretty suburban cul-de-sac. Looking past the perfect picket fences, she and her team are startled by the lives spinning out of control and the ever-changing suspect roster.
When a wealthy tycoon's much younger new wife, Julie Loeb, is shot at a family deer-hunting outing, suspects abound. The tycoon, Martin Loeb, is such a likely suspect that Megan openly accuses him and is fired from the case by Kate, at the request of the highly-influential Martin. Martin's ex-wife, Alexandra Loeb, had a clear financial motive, but his grown children are also potential suspects. Megan and Kate's relationship grows ever chillier, but Megan's new case, that of a bludgeoned man killed in a bad neighborhood, brings her right back to the initial murder.
Megan investigates the death of a young nanny run down by a car and discovers that her 5-year-old charge has been kidnapped – and requires medication. A handsome FBI agent, Derek Ames, is assigned to the case. Meanwhile, Bud comes under scrutiny when an interrogation of the prime suspect in the kidnapping takes a wrong turn; and Megan's mother, Joan, offers to help her, but Megan is leery - is it just a PR stunt for her mother's re-election?
A man, presumed dead, who walks off Ethan's examination table leads the team to a shocking discovery.
Peter stumbles upon a house fire in progress before the fire department arrives and is able to rescue a young woman. When Megan goes to the scene of the fire, she discovers that there is another victim who perished in the fire. This dismays Peter, who didn't know there was someone else in the house and now has a personal attachment to this case. As Megan begins her investigation, she is usurped by veteran arson investigator Ray Easton and his young colleague, Skip, who challenge her at every step. When Megan complains to her boss, Kate wryly remarks that people …
A champion equestrian is killed and potential drug use is suspected, but when Megan's daughter, who also rides, overhears details of the case, she leads the team to a clue and possibly the murderer.
When a popular 17-year-old high school student is found dead after a rave, the team must decipher various unknown drugs in his system and multiple bruises to figure out the cause of death. Meanwhile, Meghan is finally starting to date again after the divorce, but her ex-husband springs some shocking news on her and her daughter, causing tension at home.
A woman is found in the river. They discover she bled out but there's no blood where they found her. They learn that she was poisoned. They learn she's a pharmaceutical rep. They learn that she was having an affair with a married doctor. He tells them she died while they were together. He was afraid so he threw her body in the river and cleaned up where they were. When he tells them how she died helps them to find out what happened to her. And Megan is making a room for her daughter but is not asking her what she wants.
A murdered young woman's body turns up in place of a medical school cadaver during class, leaving Megan to rely on the aid of the star student to help solve the case.
When a recent lottery winner is found brutally murdered, everyone becomes a suspect.
After a bride plummets to her death on her wedding day, everyone from the angry ex boyfriend to the over bearing father is a suspect. But just like a bride herself, Megan pays attention to every tiny detail until she can solve the crime. Meanwhile, Ethan is falling hard for the new girl, Dani, but she already seems to have found a love interest with someone else on the team.
When an undercover cop is found executed at a truck stop, the search for the killer hits close to home.
When a woman, recently found innocent of her child's murder by Judge Joan Hunt, is killed, Megan and her staff must find who did it. A sensationalistic reporter impedes their progress. Meanwhile, because of the controversy surrounding the case, Judge Hunt is voted out of office.
When the owner of a family owned and operated Italian restaurant turns up dead in the freezer, Dr. Hunt and the team take a closer look into family matters. Meanwhile, Peter must face his own haunted past.
After a car accident reveals a dead body in the trunk, the team is led to another body, leaving them with two cases to solve, while Megan is reconnected with an old acquaintance and Kate's job is threatened.
When the parents of a perfect family are murdered and discovered by their son, the team soon realizes that things are not as it seems. Meanwhile Curtis struggles with his new position, and Megan's new love life heats up.
When two young girls are in a tragic car accident, one is left in critical condition and the other is found dead at the scene. As Megan and her team investigate the case, however, they realize there has been an awful mistake. Not only was the wrong girl pronounced dead, but the car accident may not have been the actual cause of death.